Gout, Steatorrhoea, and Megaloblastic Anaemia.

نویسنده

  • J G Lewis
چکیده

Examination in Hospital.-He was febrile and pale with a smooth tongue. No splenic enlargement was detected. There were no significant neurological signs. The haemoglobin level was 33 per cent., red blood count 1,360,000/c.mm., colour index 1-27, average red cell diameter 7 8,t, and white blood count 5,800/c.mm. There was marked anisocytosis, poikilocytosis, scanty platelets, and 1 per cent. reticulocytes. The sternal marrow was richly cellular with normal myelopoiesis, and there was marked erythroid hyperplasia with numerous early and intermediate normoblasts, but no megaloblasts or macronormoblasts. The gastric contents contained free acid. A barium meal reached the caecum in one hour, but showed no clumping or mucosal abnormality. During his stay in hospital he gave a recent history of gout in his big toes, with attacks lasting up to one week. A radiograph of his feet, however, showed no evidence of gout. He was treated with blood transfusion, liver injections, and vitamin B12, and gradually improved. By June, 1953, his haemoglobin level was 83 per cent.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Malignant Gout with Tophaceous Small Intestine and Megaloblastic Anaemia.

Gout, like diabetes, is worst in youth. Often impossible to control by uricosuiric drugs, it may cause premature death. Such was the case of a man described by Kersley, Mandel, and Jeffrey (1950). He developed gout at 18 years, became crippled at 21, and died at 24 from bronchopneumonia, associated with a tophus in the atlas vertebra. His brother, who came under our care, also developed gout at...

متن کامل

Howell-Jolly bodies in idiopathic steatorrhoea.

Large numbers of Howell-Jolly bodies were found in the bone marrow and peripheral blood, both before and after corrective haematinic therapy, in three patients with idiopathic steatorrhoea with associated splenic atrophy, who presented with megaloblastic anaemia. The proportion of erythrocytes containing Howell-Jolly bodies was much higher in these patients when compared with the number found i...

متن کامل

Diagnostic value of the serum folate assay.

The diagnostic value of the serum folate assay has been assessed in 90 patients, each of whom had a macrocytic anaemia and a low serum vitamin B(12) level. Twenty-nine (32%) patients were found to have anaemia due primarily to folate deficiency. The cause of the low serum vitamin B(12) levels is uncertain in the 22 (25%) patients with normal or borderline vitamin B(12) absorption. The effect of...

متن کامل

Influence of gastric pH on gastric and jejunal flora

In the first part of this investigation 33 subjects were investigated. Ten (nos. I to 10) had previously undergone operations for peptic ulcer (eight Billroth II and one Billroth I partial gastrectomies and one gastroenterostomy) (Table I). Seven patients (nos. 11 to 17) suffered from idiopathic steatorrhoea (Table II). Eight patients (nos. 18 to 25) had pernicious anaemia, untreated or treated...

متن کامل

Influence of gastric pH on gastric and jejunal flora.

In the first part of this investigation 33 subjects were investigated. Ten (nos. I to 10) had previously undergone operations for peptic ulcer (eight Billroth II and one Billroth I partial gastrectomies and one gastroenterostomy) (Table I). Seven patients (nos. 11 to 17) suffered from idiopathic steatorrhoea (Table II). Eight patients (nos. 18 to 25) had pernicious anaemia, untreated or treated...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Annals of the rheumatic diseases

دوره 21 3  شماره 

صفحات  -

تاریخ انتشار 1962